PSP-Progressive supranuclear palsy

Progressive supranuclear palsy (also known as PSP, or Steele-Richardson-Olszewski syndrome), is a rare degenerative disease, the most common atypical parkinsonian movement disorder that affect movement, balance, and vision. At the beginning, sufferers lose their balance, such as unsteady walking, or abrupt and unexplained falls without loss of consciousness. They have general slowing of movement, changes in personality, and visual symptoms. Later, they will suffer slurring of speech, dementia, difficulty in swallowing, and difficulty in moving eyes, particularly in the vertical direction. They are unable to look up or down. Some present contracture of facial muscles, poor eyelid movements, and a backward tilt of head with stiffening of neck muscles.

Currently, there is no effective treatment for progressive supranuclear palsy. Some medications may manage some symptoms temporarily. Stem cell treatment is a new attempt for PSP.

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